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Moreover, vitamin D upregulates TRAF3 expression to inhibit the noncanonical NF-B2 pathway, alleviating the inflammatory state in end-stage renal disease (ESRD) patients and animal models (22)

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Healthcare professionals should assess B12 status in high-risk patients and consider supplementation or intramuscular injections if deficiency is confirmed

In this model, behavioral experiments were performed on day 2 (randomization), 7 and 10